BIOL 249 HW – Genetics

microbiology multi-part question and need the explanation and answer to help me learn.

The purpose of this homework assignment is to demonstrate your mastery on central dogma of the cell, DNA -> RNA -> Protein via transcription and translation. You will also learn to identify the various types of mutations that can occur, and how they occur.

Requirements: 2 pages
General Microbiology Bio 229 Name
Genetics Problem Worksheet
Answer the following question on this paper:
For the following Prokaryotic DNA strand, show the mRNA which would be transcribed from this strand and show the polypeptide which would be produced if the mRNA were translated. (See a codon chart for reference).
3’ 5’
DNA strand: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 G A C C T A C G T G C A T T T G G T T C T T C C A A T C G
mRNA:
Polypeptide:
In the DNA strand shown in the previous problem, what would be the effect on the resulting polypeptide if the following occurred? Be specific ie write out the result: Write codon and amino acid pre and post mutation.
Changing G to A at base 17?
Changing G to C at base 16?
Changing T to G at base 13?
Delete base 20?
What are the names of these types of mutations?
Mutation A
Mutation B
Mutation C
Mutation D
On the DNA strand above, circle the areas that would be affected by UV radiation.
Why doesn’t UV light kill all of the bacterial cells?

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